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Amines REACH

Tetrabutylammonium bromide

CAS Number
1643-19-2
EC Number
216-699-2
Chemical Formula
C16H36N.Br
Molecular Weight
322.37 g/mol

Description

Tetrabutylammonium bromide (CAS 1643-19-2 ), commonly sourced under the abbreviation TBAB, is a quaternary ammonium salt used primarily as a phase-transfer catalyst and reagent in chemical synthesis. Its ability to shuttle anions between immiscible phases makes it a practical tool for improving reaction efficiency and yield in multi-step manufacturing processes across various industrial sectors. In pharmaceutical manufacturing, TBAB accelerates nucleophilic substitution and alkylation reactions, reducing processing time and solvent consumption in active pharmaceutical ingredient (API) synthesis. Personal care formulators use it as a conditioning and antimicrobial agent in rinse-off and leave-on products where quaternary ammonium activity is required for the final formulation. It also functions as a catalyst precursor in polymer and specialty chemical production, where controlled ionic transfer between organic and aqueous phases is critical to process consistency. In research and fine chemical synthesis, TBAB supports the preparation of ionic liquids and serves as a co-catalyst in carbon dioxide fixation reactions for sustainable chemistry. Tetrabutylammonium bromide is supplied as a white crystalline powder or granular solid. It is available in technical and high-purity reagent grades for diverse laboratory and industrial uses. Pharmaceutical-grade material meets specifications relevant to API and excipient manufacturing. Packaging typically ranges from kilogram-scale laboratory quantities to bulk industrial lots. Contact us for supply of Tetrabutylammonium bromide Request Quote

Other Names (Synonyms)

tetra-N-butylammonium bromide | TBAB | N,N,N-tributyl-1-butanaminium bromide | 1-Butanaminium, N,N,N-tributyl-, bromide (1:1) | N,N,N-tributylbutan-1-aminium bromide | VJZ168I98R | 1-Butanaminium, N,N,N-tributyl-, bromide | TBAB SUMQUAT 6065

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point100-102 °C
Boiling Point102 °C
Density1.039 g/mL at 25 °C
Flash Point100°C
Appearancewhite crystals or powder
ColorWhite to slightly cream
OdorAmine like
FormCrystalline Powder
Water Solubility600 g/L (20 ºC)
Vapor Pressure0Pa at 25℃
Refractive Indexn20/D 1.422
pH3.5 to 7.0 (50 g/L, 25 ℃)
Log P0.839 at 25℃

Safety & Handling

Warning
GHS07· IrritantGHS08· Health HazardGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H320Causes eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29239000
Storage Class11 - Combustible Solids
WGK (Germany)3