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p-Cresol

CAS Number
106-44-5
EC Number
203-398-6
Chemical Formula
C7H8O
Molecular Weight
108.14 g/mol

Description

p-Cresol (CAS 106-44-5 ), also known by its FEMA 2337 designation in flavor applications, is a methylphenol derivative used across fragrance, pharmaceutical, and industrial chemistry. It acts as a chemical building block and functional additive, serving as a precursor, preservative, and stabilizer depending on the specific formulation context and industrial requirements. In flavors and fragrances, it contributes phenolic, smoky, and medicinal character to food flavorings and fine fragrance compositions at controlled use levels for optimal sensory profiles. Pharmaceutical manufacturers use it as an intermediate in synthesizing antioxidants, disinfectants, and active pharmaceutical ingredients, ensuring high performance in medical applications. In coatings and polymer systems, it functions as an antioxidant stabilizer to protect resins and elastomers from oxidative degradation during processing and throughout their service life. Personal care formulators incorporate it at low concentrations for its preservative and antimicrobial properties in select cosmetic systems, maintaining product integrity and safety. The product is supplied as a liquid or low-melting solid, depending on temperature conditions during handling. It is available in technical grade for industrial and coating applications. Higher-purity grades are available for pharmaceutical intermediate and flavor use. Packaging typically ranges from drums to ISO containers for bulk procurement and global distribution. Contact us for supply of p-Cresol Request Quote

Other Names (Synonyms)

para-cresol | 4-methylphenol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point35.5 °C
Boiling Point201.8 °C
Density1.0185 g/cm³ @ Temp: 40 °C
Flash Point193 °F
AppearanceCresol is a mixture of the three isomeric cresols, o-, m-, and p-cresol. Cresols are slightly soluble in water. m-Isomer: Colorless or yellow liquid with characteristic odor.
ColorColorless to light yellow, may darken on exposure to light
Odorat 0.10 % in dipropylene glycol. phenolic narcissus animal mimosa
FormCrystalline Solid or Liquid
Water Solubility20 g/L (20 ºC)
Vapor Pressure1 mm Hg ( 20 °C)
Refractive IndexnD20 1.5395
Log P1.94

Safety & Handling

Danger
GHS05· CorrosiveGHS06· ToxicGHS08· Health HazardGHS07· IrritantGHS09· Environment

Hazard Statements

H301Toxic if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation
H351Suspected of causing cancer
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects H301+
H311Toxic if swallowed or in contact with skin

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P364Take off immediately all contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29071200
UN Number3455
ADR Class6.1
Packing GroupII
Storage Class6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany)1