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2-methyltetrahydrofuran

CAS Number
96-47-9
EC Number
202-507-4
Chemical Formula
C5H10O
Molecular Weight
86.13 g/mol

Description

2-Methyltetrahydrofuran (CAS 96-47-9 ), commonly abbreviated as 2-MeTHF, is a cyclic ether solvent derived from renewable feedstocks such as furfural. It functions as a direct replacement for tetrahydrofuran in synthesis and extraction processes. This solvent offers improved water immiscibility and a higher boiling point compared to traditional alternatives. In pharmaceutical manufacturing, it is used as a reaction solvent for Grignard reactions and organolithium chemistry. Its tolerance to aqueous workup conditions simplifies downstream processing during catalytic hydrogenations. Its partial bio-based origin supports green chemistry compliance in API synthesis, which is a decisive factor in supplier qualification. Personal care formulators use it as a carrier solvent for active ingredient dissolution and extraction steps during raw material processing. A minor application exists in flavors and fragrances for specific ethereal notes. The product is supplied as a clear liquid in standard packaging ranging from drums to ISO tank quantities. Technical grade and high-purity anhydrous grades are the most commonly traded specifications for industrial use. Stabilized variants are available for extended storage to prevent peroxide formation. Buyers should confirm inhibitor type and water content specifications when sourcing for sensitive synthetic applications to ensure performance. Contact us for supply of 2-methyltetrahydrofuran Request Quote

Other Names (Synonyms)

2-Methyloxolane | Tetrahydro-2-methylfuran | Furan, tetrahydro-2-methyl- | MTHF | FCD0VD8ALF | 2-MeTHF

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-136 °C
Boiling Point78-80 °C
Density0.847 g/cm³ @ Temp: 25 °C
Press750 Torr
Flash Point10.4 °F
Appearanceliquid
ColorClear colorless
FormLiquid
Water Solubility15 g/100 mL (25 C)
Vapor Pressure136 hPa (20 °C)
Refractive Indexn 20/D 1.406(lit.)
Log P1.1 at 20℃

Safety & Handling

Danger
GHS02· FlammableGHS05· CorrosiveGHS07· Irritant

Hazard Statements

H225Highly Flammable liquid and vapor
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29321900
UN Number2536
ADR Class3
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)2