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Coenzyme a

CAS Number
85-61-0
EC Number
201-619-0
Chemical Formula
C21H36N7O16P3S
Molecular Weight
767.5 g/mol

Description

Coenzyme A (CAS 85-61-0 ), commonly abbreviated as CoA or referenced as CoASH and HSCoA in biochemical sourcing contexts, is a critical cofactor involved in acyl group transfer reactions across metabolic pathways. In commercial and research settings, it functions as a biochemical reagent enabling enzymatic synthesis, assay development, and the production of acylated intermediates for various industrial applications. In pharmaceutical manufacturing, CoA supports the synthesis of acetyl-CoA-dependent intermediates used in active pharmaceutical ingredient development and metabolic pathway research for drug discovery. Biotechnology and life sciences buyers source it primarily for in vitro enzyme activity assays, coenzyme-dependent reaction screening, and metabolic flux studies in laboratory environments. Cosmetic formulators incorporate CoA-based systems into advanced skin care actives targeting cellular energy metabolism and moisture retention at the formulation level for high-end products. It also serves as a reference standard and substrate in diagnostic kit manufacturing, where consistent purity and activity are procurement-critical requirements for quality control. Coenzyme A is supplied as a lyophilized powder or as a sodium salt form, with the free acid and lithium salt variants also available depending on specific application requirements. Standard grades include research-grade and high-purity biochemical-grade material, with specifications typically defined by enzymatic activity rather than conventional chemical purity alone. Contact us for supply of Coenzyme a Request Quote

Other Names (Synonyms)

HSCoA | CoASH | CoA | Zeel | SAA04E81UX | 3'-phosphoadenosine-(5')diphospho(4')pantatheine | Reduced CoA | Thiol-CoA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Density1.96±0.1 g/cm3(Predicted)
Appearanceyellowish lyophilisate
ColorWhite to light yellow
FormA crystalline solid
Log P-4.358 (est)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2933299090
Storage Class11 - Combustible Solids
WGK (Germany)3