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Diazolidinyl urea

CAS Number
78491-02-8
EC Number
278-928-2
Chemical Formula
C8H14N4O7
Molecular Weight
278.22 g/mol

Description

Diazolidinyl urea (CAS 78491-02-8 ), also known commercially as Germall 11, is a formaldehyde-releasing preservative used across personal care and pharmaceutical formulations. It provides broad-spectrum antimicrobial protection against bacteria, yeast, and mold, extending the shelf life of water-containing products in various industrial applications. In rinse-off and leave-on cosmetics, including lotions, shampoos, and conditioners, it is used at low concentrations to prevent microbial contamination throughout the product lifecycle. Liquid and gel-based personal care formulations benefit from its water solubility, allowing straightforward incorporation without disrupting the stability of the emulsion system. Pharmaceutical topical preparations such as creams and ointments rely on it to meet preservation efficacy requirements under standard challenge testing protocols for safety. It is frequently paired with parabens or other co-preservatives to achieve broader coverage and reduce the required use level of each individual ingredient in the final blend. Diazolidinyl urea is supplied as a white to off-white powder. It is available in cosmetic-grade and pharmaceutical-grade specifications, conforming to USP and BP monographs. Standard packaging ranges from kilogram quantities for formulators to bulk drum supply for larger manufacturing operations, ensuring consistent quality for all industrial clients. Contact us for supply of Diazolidinyl urea Request Quote

Other Names (Synonyms)

N,N'-Bis(hydroxymethyl) urea | Germall 11 | Imidazolidinyl urea 11 | N9VX1IBW6K | H5RIZ3MPW4 | Germall II | Germaben II-E

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Boiling Point421.04°C (rough estimate)
Density1.4734 (rough estimate)
Appearancewhite powder
ColorWhite to Off-White
FormSolid
Water Solubility1000g/L at 20℃
Vapor Pressure0Pa at 20℃
Refractive Index1.6590 (estimate)
Log P0.9 at 20℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339900
WGK (Germany)2