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Bispinacolatodiborane

CAS Number
73183-34-3
EC Number
615-925-0
Chemical Formula
C12H24B2O4
Molecular Weight
253.9 g/mol

Description

Bispinacolatodiborane (CAS 73183-34-3 ), also known as B2pin2, is a diboron reagent used as a key borylation source in synthetic chemistry and pharmaceutical manufacturing. It delivers two pinacolboronate ester units in a single reagent, enabling efficient introduction of boronic ester groups into organic molecules without requiring air-sensitive handling. In pharmaceutical synthesis, B2pin2 is the preferred reagent for palladium-catalyzed Miyaura borylation, converting aryl and vinyl halides into pinacol boronate esters. These serve as intermediates for Suzuki–Miyaura cross-coupling in active pharmaceutical ingredient (API) production. Specialty polymer manufacturers use it to introduce boron-functional groups. This enables controlled crosslinking and stimuli-responsive material design. In fine chemical and agrochemical synthesis, it supports the preparation of borylated building blocks. Research-scale and contract manufacturing operations in the textile and paper sectors also employ it for surface-functionalizing agents derived from boronate chemistry. Bispinacolatodiborane is supplied as a white to off-white crystalline solid. It is available in research quantities through to multi-kilogram lots for industrial use. Purity grades typically range from 97% to 99%+ to meet pharmaceutical intermediate and fine chemical manufacturing requirements for high-performance applications. Contact us for supply of Bispinacolatodiborane Request Quote

Other Names (Synonyms)

Bis(pinacolate)diborane | 4,4,5,5-tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Bis(pinacolato)diborane

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point139-140 °C
Boiling Point222.6±7.0 °C(Predicted)
Density0.98
Appearancewhite crystal powder
ColorWhite
FormPowder or Platelets
Water SolubilitySoluble in tetrahydrofuran, dichloromethane, toluene, hexane and heptane. Insoluble in water.

Safety & Handling

Danger
GHS05· CorrosiveGHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29209090
Storage Class11 - Combustible Solids
WGK (Germany)3