HomeProducts

Pyridine-borane

CAS Number
110-51-0
EC Number
203-773-4
Chemical Formula
C5H8BN
Molecular Weight
92.94 g/mol

Description

Pyridine-borane (CAS 110-51-0 ) is a stabilized borane complex that delivers controlled hydride-reducing activity under mild conditions. It functions as a selective reducing agent in synthetic chemistry. This reagent offers greater handling safety and solution stability than free borane reagents. In pharmaceutical manufacturing, it reduces imines and iminium ions in reductive amination reactions. This is a critical step in producing active pharmaceutical ingredients and chiral intermediates. Electronics manufacturers use it in electroless plating baths and surface treatment processes. It is utilized where controlled boron deposition is required. Biotechnology researchers rely on it for reductive amination of biomolecules including proteins, peptides, and oligosaccharides. Selectivity and aqueous compatibility are priorities in these applications. It also serves synthetic chemistry workflows requiring mild reduction of aldehydes and ketones without over-reduction. This prevents the degradation of sensitive functional groups during the process. The product is supplied as a colorless to pale yellow liquid, typically in concentrations around 8 M in solution. It is available in research quantities through to multi-kilogram lots for process-scale use. Technical and high-purity grades are offered to meet synthetic and manufacturing requirements. Purity specifications are commonly at 97% or above. This ensures the material meets the rigorous standards necessary for pharmaceutical and industrial chemical production cycles. Contact us for supply of Pyridine-borane Request Quote

Other Names (Synonyms)

Pyridine-borane (1:1) | Trihydro(pyridine)boron | Borane-pyridine (1:1) | 8JXE4C7UEX | RefChem:177566 | Boron, trihydro(pyridine)-, (T-4)-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point46-47 °C
Boiling Point102 °C (0.37505 mmHg)
Density0.929 g/mL at 20 °C
Flash Point70 °F
Appearanceclear to slightly hazy colorless to amber liquid
ColorClear to slightly hazy colorless to amber
FormLiquid
Water Solubilityreacts slowly
Refractive Indexn 20/D 1.532(lit.)

Safety & Handling

Danger
GHS02· FlammableGHS06· Toxic

Hazard Statements

H225Highly Flammable liquid and vapor
H301Toxic if swallowed
H310Fatal in contact with skin
H311Toxic in contact with skin
H330Fatal if inhaled H310+
H330Fatal in contact with skin or if inhaled

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P364Take off immediately all contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.

Trade & Regulatory

HS Code29333990
UN Number1992
ADR Class3
Packing GroupII
WGK (Germany)2