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1-methylimidazole

CAS Number
616-47-7
EC Number
210-484-7
Chemical Formula
C4H6N2
Molecular Weight
82.10 g/mol

Description

1-Methylimidazole (CAS 616-47-7 ), commonly abbreviated as NMI, is a nitrogen-containing heterocyclic compound used industrially as a catalyst, curing agent, and synthesis intermediate. Its reactivity toward electrophiles and metal coordination makes it a practical building block across pharmaceutical manufacturing, polymer chemistry, and specialty coatings. In epoxy resin systems, NMI functions as a latent curing agent and cure accelerator, enabling controlled crosslinking in electrical laminates, adhesives, and industrial coatings. Pharmaceutical manufacturers use it as a coupling catalyst in peptide synthesis and acylation reactions, where it improves reaction efficiency and yield at scale. NMI is a key precursor in the synthesis of ionic liquids, particularly imidazolium-based salts used as reaction media or electrolytes in battery and electrochemical applications. It also serves as a ligand or co-catalyst in organometallic processes, supporting active pharmaceutical ingredient (API) production and fine chemical synthesis. 1-Methylimidazole is supplied as a colorless to pale yellow liquid in drums, IBCs, and bulk quantities. Technical grade is the standard commercial offering for most uses. High-purity grades are available for pharmaceutical and electronic applications. Buyers should confirm water content and color specifications when sourcing for sensitive catalytic applications. Contact us for supply of 1-methylimidazole Request Quote

Other Names (Synonyms)

N-Methylimidazole | 1-Methyl-1H-imidazole | 1H-Imidazole, 1-methyl- | IMIDAZOLE, 1-METHYL- | P4617QS63Y | 1-methyl-1H-imidazol-3-ium | N1-Methylimidazole | NMI

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-6 °C
Boiling Point198-199 °C
Density1.035 g/cm³ (liquid)
Flash Point198 °F
AppearanceClear colorless to yellow liquid
ColorClear colorless to yellow
FormLiquid
Water SolubilityMiscible with water.
Vapor Pressure0.4 mm Hg ( 20 °C)
Refractive Indexn 20/D 1.495(lit.)
pH9.5-10.5 (50g/l, H2O, 20℃)
Log P-0.19 at 25℃

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS06· ToxicGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29332990
UN Number3267
ADR Class8
Packing GroupII
WGK (Germany)1