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p-toluenesulfonyl isocyanate

CAS Number
4083-64-1
EC Number
223-810-8
Chemical Formula
C8H7NO3S
Molecular Weight
197.21 g/mol

Description

p-Toluenesulfonyl isocyanate (CAS 4083-64-1 ), commonly known as tosyl isocyanate or PTSI, is a reactive isocyanate reagent used across coatings, adhesives, and polymer systems. It functions primarily as a crosslinking agent and moisture scavenger, reacting with hydroxyl and amine groups to build or stabilize polymer networks in various industrial applications. In polyurethane coatings and adhesives, PTSI acts as a crosslinker that improves chemical resistance and film hardness without requiring elevated cure temperatures for the final product. Sealant and elastomer formulators use it to scavenge residual moisture from systems sensitive to premature gelation, extending pot life and improving shelf stability during storage. In textile and leather finishing, it enables durable bonding of functional coatings to fiber substrates by reacting with surface hydroxyl groups to create a strong chemical bond. Plastic and polymer manufacturers incorporate PTSI as a reactive building block in specialty monomers where controlled isocyanate functionality is required for specific material properties. p-Toluenesulfonyl isocyanate is supplied as a clear to pale yellow liquid. Technical grade is the standard commercial form, with purity specifications typically ranging from 97% upward. Packaging options generally include small reagent quantities through to drum-scale volumes for industrial procurement, ensuring flexibility for both laboratory and large-scale manufacturing needs. Contact us for supply of p-toluenesulfonyl isocyanate Request Quote

Other Names (Synonyms)

Tosyl isocyanate | 4-Methylbenzenesulfonyl isocyanate | p-Toluenesulphonyl isocyanate | Benzenesulfonyl isocyanate, 4-methyl- | Additive ti | H9004FJX6V | p-Toluenesulfonic acid, anhydride with isocyanic acid | PTSI

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point188-189 °C
Boiling Point75-80 °C @ Press: 0.05-0.1 Torr
Density3.877 g/cm³ @ Temp: 827 °C
Flash Point>230 °F
Appearanceclear liquid
ColorClear colorless to yellow
Odoracrid odor
FormLiquid
Water Solubilityreacts
Vapor Pressure1 mm Hg ( 100 °C)
Refractive Indexn 20/D 1.534(lit.)
Log P0.6 at 30℃

Safety & Handling

Danger
GHS07· IrritantGHS08· Health HazardGHS06· Toxic

Hazard Statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H330Fatal if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H372Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P316Get emergency medical help immediately.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29309090
UN Number2206
ADR Class6.1
Packing GroupIII
Storage Class10 - Combustible liquids
WGK (Germany)1