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Sodium thioglycolate

CAS Number
367-51-1
EC Number
206-696-4
Chemical Formula
C2H4O2S.Na
Molecular Weight
114.10 g/mol

Description

Sodium thioglycolate (CAS 367-51-1 ), commonly abbreviated as NATG, is the sodium salt form of thioglycolic acid used across personal care, textile, and industrial processing markets. It functions primarily as a reducing agent and depilatory active, breaking disulfide bonds in keratin-containing substrates to enable chemical modification of hair and wool fibers. In personal care manufacturing, NATG is the active ingredient in chemical depilatory creams and cold wave permanent solutions, where it disrupts the protein structure of hair. Leather processors use it during the unhairing stage to remove hair from hides without mechanical damage, improving throughput and hide quality for various industrial applications. Textile producers apply it in wool treatment processes to reduce fiber stiffness and improve dye uptake. In analytical and industrial chemistry, it acts as a stabilizing agent. It also serves as a metal chelator in formulations requiring control of oxidative degradation. Sodium thioglycolate is supplied as an aqueous solution with concentrations from 40% to 58%. Technical and cosmetic grades are the most commercially available, with cosmetic-grade material subject to purity thresholds aligned with regional regulatory requirements. Bulk liquid supply in drums or IBCs is standard for industrial buyers. This ensures efficient handling and storage for large-scale manufacturing and chemical processing facilities. Contact us for supply of Sodium thioglycolate Request Quote

Other Names (Synonyms)

Thioglycollic acid, sodium salt | Thioglycolate sodium | Sodium 2-sulfanylacetate | Sodium 2-mercatoethanoate | Mercaptoacetic acid, sodium salt | Sodium thioglycollate | Sodium mercaptoacetate | sodium sulfanylacetate | NATG

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point>300 °C (lit.)
AppearanceWhite solid
ColorWhite powder
OdorStench odour
Formsolid
Water Solubilitysoluble
Vapor Pressure<0.1 hPa (25 °C)
pH6.7 (100g/l, H2O, 20℃)
Log P-2.99 at 20℃

Safety & Handling

Danger
GHS05· CorrosiveGHS06· ToxicGHS07· IrritantGHS08· Health HazardGHS09· Environment

Hazard Statements

H290May be corrosive to metals
H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H330Fatal if inhaled
H331Toxic if inhaled
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P234Keep only in original packaging.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P390Absorb spillage to prevent material damage.
P391Collect spillage.
P405Store locked up.
P406Store in a corrosion-resistant/… container with a resistant inner liner.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29309070
WGK (Germany)1