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Potassium thioglycolate

CAS Number
34452-51-2
EC Number
252-038-4
Chemical Formula
C2H4O2S.K
Molecular Weight
130.21 g/mol

Description

Potassium thioglycolate (CAS 34452-51-2 ), commonly abbreviated as K-TGA, is the potassium salt form of thioglycolic acid used across cosmetic and industrial processing applications. It functions as a reducing agent and keratin-disulfide bond disruptor. This chemical enables the modification of protein-based substrates. Procurement teams source it as a more pH-compatible alternative to ammonium thioglycolate in formulations requiring tighter alkalinity control. In professional hair depilation and chemical straightening products, K-TGA breaks disulfide bonds in hair keratin to reshape or remove the fiber structure. This makes it a critical component in salon-grade hair treatments. Leather processing operations use it as a depilatory agent to remove hair from hides during the beamhouse stage. This application helps in reducing the industrial reliance on traditional sulfide-based chemistries. Textile processing applications include wool fiber modification, where controlled reduction of cystine linkages alters shrink resistance and surface texture. It also functions as a chelating agent in specific formulations. The product is utilized where sequestration of metal ions is needed to stabilize the active system. Potassium thioglycolate is supplied as an aqueous solution, with concentration typically ranging around 40–50% active content. Technical and cosmetic-grade specifications are the most commonly available. Cosmetic-grade material meets purity requirements aligned with personal care manufacturing standards for safety and performance. Bulk liquid supply in drums or IBC containers is the standard commercial format for industrial buyers. This ensures efficient handling and storage for large-scale manufacturing and processing facilities. Contact us for supply of Potassium thioglycolate Request Quote

Other Names (Synonyms)

Acetic acid, mercapto-, monopotassium salt | Potassium 2-mercaptoacetate | XP5WZO5W6H | Acetic acid, 2-mercapto-, potassium salt (1:1) | Potassium Mercaptoacetate | Mercaptoacetic Acid Potassium Salt | Thioglycolic Acid Potassium Salt | K-TGA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point226-229 °C
Density1.365[at 20℃]
AppearanceClear faintly pink solution
ColorClear faintly pink
FormSolution
Water Solubility785.8g/L at 20℃
Vapor Pressure0.001Pa at 25℃
Log P-2.99 at 20℃

Safety & Handling

Danger
GHS05· CorrosiveGHS06· ToxicGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H290May be corrosive to metals
H301Toxic if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P234Keep only in original packaging.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in a corrosion-resistant/… container with a resistant inner liner.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29309099