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Amines REACH

Polyhexamethylene biguanide

CAS Number
32289-58-0
EC Number
608-723-9
Chemical Formula
(C8H17N5)n.xClH
Molecular Weight
213.32 g/mol

Description

Polyhexamethylene biguanide (CAS 32289-58-0 ), commonly known as PHMB or polyhexanide, is a polymeric antimicrobial agent used across industrial, healthcare, and consumer applications. It functions as a broad-spectrum biocide and preservative, effective against bacteria, fungi, and certain viruses at low use concentrations. Poly(hexamethylenebiguanide) hydrochloride is the most commercially distributed salt form. In wound care and medical device manufacturing, polyhexanide is the active ingredient in antiseptic irrigations, wound dressings, and contact lens solutions. These applications rely on its high efficacy. Personal care formulators incorporate PHMB as a preservative in rinse-off and leave-on products including shampoos, wipes, and skin cleansers. It ensures product stability and consumer safety during use. Textile and leather processors apply it to impart durable antimicrobial protection to fabrics, nonwovens, and treated surfaces. This prevents odor and degradation caused by microbial growth in materials. Water treatment operations use PHMB to control microbial growth in swimming pools, cooling towers, and industrial process water. It serves as a stable and effective alternative to chlorine-based biocides. Polyhexamethylene biguanide is supplied as an aqueous solution, typically at 20% active concentration. Grades include technical, cosmetic, and pharmaceutical quality for various industrial requirements. Buyers should confirm active content, molecular weight distribution, and regulatory compliance when sourcing. This includes checking biocidal product regulations and cosmetic approvals for regulated end uses. Contact us for supply of Polyhexamethylene biguanide Request Quote

Other Names (Synonyms)

N'-[6-[(n'-methylcarbamimidoyl)amino]hexyl]ethanimidamide | Poly(hexamethylenebiguanide) hydrochloride | Polyhexanide | PHMB

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

ColorWhite to off-white
FormSolid

Safety & Handling

Danger
GHS05· CorrosiveGHS06· ToxicGHS08· Health HazardGHS09· EnvironmentGHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H330Fatal if inhaled
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.