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Chlorhexidine gluconate

CAS Number
18472-51-0
EC Number
242-354-0
Chemical Formula
C22H30Cl2N10.2C6H12O7
Molecular Weight
897.8 g/mol

Description

Chlorhexidine gluconate (CAS 18472-51-0 ), commonly abbreviated as CHG and also known as chlorhexidine digluconate, is a broad-spectrum antimicrobial agent used across pharmaceutical and personal care manufacturing. It delivers sustained bactericidal and antifungal activity, making it a preferred active ingredient in antiseptic and preservative formulations. In healthcare settings, CHG is the active ingredient in surgical scrubs. It is used in pre-operative skin preparation products and wound care formulations. Oral care products such as prescription-strength mouth rinses rely on CHG for its substantive binding to oral mucosa. This provides prolonged antimicrobial action against plaque-forming bacteria. Personal care formulators incorporate it into hand sanitizers, intimate hygiene products, and medicated cleansers. It is used where preservative efficacy and skin compatibility are both required. It also functions as a preservative in ophthalmic solutions and contact lens care products at low concentrations. Chlorhexidine gluconate is supplied primarily as an aqueous solution, with 20% and 5% concentrations being the most common commercial forms. Pharmaceutical-grade material is available to USP standards. The material is also available to BP and Ph. Eur. specifications. Bulk supply is standard for industrial and pharmaceutical buyers, with solution concentration being a key procurement parameter. Grade specification remains a critical factor for buyers in the chemical industry. These standards ensure the material meets the rigorous safety requirements for medical and consumer applications. Contact us for supply of Chlorhexidine gluconate Request Quote

Other Names (Synonyms)

Peridex | Hibiclens | chlorhexidine digluconate | chlorhexidine di-D-gluconate | chlorhexidine D-digluconate | 1,1'-hexamethylene bis(5-(p-chlorophenyl)biguanide), digluconate | Dyna-hex | Bioscrub | CHG

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Density1.06 g/mL at 25 °C(lit.)
AppearanceAlmost colourless or pale-yellowish liquid.
ColorColorless
FormLiquid
Water Solubility750g/L at 20℃
Vapor Pressure0.005Pa at 25℃
Log P-1.81 at 20.7℃

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS09· EnvironmentGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary Statements

P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P317Get emergency medical help.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P403Store in a well-ventilated place.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P316Get emergency medical help immediately.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29252900
UN Number3082
ADR Class9
Packing GroupIII
Storage Class12 - Non Combustible Liquids