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Dabigatran

CAS Number
211914-51-1
EC Number
N/A
Chemical Formula
C25H25N7O3
Molecular Weight
471.5 g/mol

Description

Dabigatran (CAS 211914-51-1 ), also referenced under the development code BIBR-953, is a direct thrombin inhibitor used as an active pharmaceutical ingredient in anticoagulant drug development. It functions as the pharmacologically active moiety in oral anticoagulant formulations targeting thromboembolic conditions. Dabigatran is the active ingredient in finished dosage form development for stroke prevention and venous thromboembolism treatment, typically formulated as the etexilate prodrug salt for oral bioavailability. Pharmaceutical manufacturers source it as a reference standard or synthetic intermediate during API characterization, method validation, and quality control workflows. Research institutions and contract development organizations use it in pharmacokinetic studies. It also serves as a benchmark compound in assay development for thrombin inhibition screening programs. Supplied as a solid powder, it is available in research-grade and pharmaceutical-grade specifications suited to analytical and development applications. Purity grades aligned with reference standard requirements are the most commonly sourced forms in the B2B market. Packaging ranges from milligram quantities for laboratory use to larger quantities supporting API development pipelines. Our supply chain ensures that the material meets rigorous internal quality benchmarks. This product is intended for laboratory research and pharmaceutical manufacturing purposes only, ensuring consistency across various batch requirements. Contact us for supply of Dabigatran Request Quote

Other Names (Synonyms)

Pradaxa | BIBR-953 | Pradaxa (dabigatran) | BIBR 953 ZW | I0VM4M70GC

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point276-277 °C
Boiling Point797.1±70.0 °C(Predicted)
Density1.38±0.1 g/cm3(Predicted)
ColorWhite to Brown
FormSolid

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

Storage Class11 - Combustible Solids
WGK (Germany)3