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Disodium EDTA

CAS Number
139-33-3
EC Number
205-358-3
Chemical Formula
C10H16N2O8.2Na
Molecular Weight
336.21 g/mol

Description

Disodium EDTA (CAS 139-33-3 ), also known as Na2H2EDTA and listed as E386 in food applications, is a chelating agent that binds and neutralizes metal ions in formulations and processes. By sequestering calcium, magnesium, iron, and other trace metals, it prevents discoloration, rancidity, and scale formation across a broad range of industries and finished products. In personal care and cosmetic formulations, it stabilizes emulsions and preservative systems by removing metal ions that would otherwise accelerate oxidative degradation during the shelf life. Food manufacturers use it under the E386 designation to protect canned vegetables, dressings, and seafood products from metal-catalyzed color and flavor loss during storage and processing. Water treatment and industrial cleaning operations rely on it to sequester hardness ions, improving detergent efficiency and preventing mineral deposits in various types of process equipment. In pharmaceutical manufacturing, it functions as a stabilizer in liquid dosage forms and ophthalmic preparations where trace metal contamination must be tightly controlled for safety. Disodium EDTA is supplied as a white crystalline powder or granules. Standard grades include food-grade, USP , BP , and Ph. Eur. specifications for pharmaceutical and regulated food applications. Technical grade is also available for industrial use. Bulk supply is available in bags and fiber drums, with packaging options suited to both formulation-scale and large industrial procurement. Contact us for supply of Disodium EDTA Request Quote

Other Names (Synonyms)

Na2H2EDTA | Na2-EDTA | N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt | ethylenediaminetetraacetic acid disodium salt | ethylenebis(iminodiacetic acid) disoidum salt | EDTA disodium salt (anh.) | EDTA disodium (anhydrous) | EDTA disodium (anh.) | E386

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point252 °C (decomp)
Boiling Point>100 °C
Density1.01 g/mL at 25 °C
Appearancewhite crystalline solid
Color≤5 (0.5 M)(APHA)
Odorat 100.00?%. odorless
Formsolution
Water SolubilityMiscible with water.
Vapor Pressure0Pa at 25℃
Refractive Indexn20/D 1.363
pH8.0±0.2
Log P-4.3 at 25℃

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224900
Storage Class12 - Non Combustible Liquids
WGK (Germany)2