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Amines REACH

2-Chloro-5-(trifluoromethyl)aniline

CAS Number
121-50-6
EC Number
204-475-7
Chemical Formula
C7H5ClF3N
Molecular Weight
195.57 g/mol

Description

2-Chloro-5-(trifluoromethyl)aniline (CAS 121-50-6 ), also known commercially as 3-Amino-4-chlorobenzotrifluoride or Fast Orange Salt RD, is an aromatic amine building block used across dye chemistry and agrochemical synthesis. Its halogenated and trifluoromethyl-substituted structure makes it a targeted intermediate for constructing complex active molecules in pharmaceutical manufacturing. In the textile and leather industries, it functions as a diazonium coupling component. This chemical is used to produce azo dyes with strong color fastness on fiber substrates. Agrochemical formulators use it as a key intermediate in synthesizing herbicides and fungicides where the trifluoromethyl group contributes to biological activity. The trifluoromethyl group also provides metabolic stability in various applications. Pharmaceutical manufacturers incorporate it into API synthesis routes, particularly for compounds requiring a halogenated aniline scaffold for efficacy. In coatings and adhesive systems, it supports the development of specialty resins and crosslinked polymer matrices with targeted performance profiles. This versatile chemical is supplied as a liquid or low-melting solid for industrial use. It is typically available in technical and synthesis grades to meet diverse manufacturing requirements. It is available in packaging ranging from laboratory quantities to bulk drums for large-scale industrial procurement needs. Purity specifications commonly range from 98% to 99%+ by GC, with documentation supporting pharmaceutical and agrochemical intermediate applications. Quality control ensures consistency across all batches for high-performance results. Contact us for supply of 2-Chloro-5-(trifluoromethyl)aniline Request Quote

Other Names (Synonyms)

3-Amino-4-chlorobenzotrifluoride | Benzenamine, 2-chloro-5-(trifluoromethyl)- | Fast Orange Salt RD | Orange Salt NRD | Daito Orange Salt RD | Diazo Fast Orange RD | Fast Orange Salt RDA | Fast Orange Salt RDN

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point10 °C
Boiling Point57-58 °C @ Press: 1.5 Torr
Density1.428 g/mL at 25 °C(lit.)
Flash Point75 °C
AppearanceCLEAR COLORLESS TO LIGHT YELLOW LIQUID
ColorColorless to Yellow to Green
Formclear liquid
Water Solubility11 g/L (60 ºC)
Vapor Pressure0.15 hPa
Refractive Indexn 20/D 1.499(lit.)

Safety & Handling

Warning
GHS07· IrritantGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H411Toxic to aquatic life with long lasting effects

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29214300
UN Number2810
ADR Class6.1
Packing GroupIII
Storage Class10 - Combustible liquids
WGK (Germany)2