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Hexamethyldisiloxane

CAS Number
107-46-0
EC Number
203-492-7
Chemical Formula
C6H18OSi2
Molecular Weight
162.38 g/mol

Description

Hexamethyldisiloxane (CAS 107-46-0 ), commonly referenced as HMDSO, is a low-viscosity silicone fluid used as a solvent, carrier, and surface-modifying agent across specialty chemical manufacturing. It conditions surfaces, aids dispersion of silicone-based materials, and supports film formation in coating and personal care applications. In silicone coatings and release liners, it acts as a reactive diluent. The material functions as a processing solvent, improving flow and substrate wetting during application. Personal care formulators use it as a lightweight carrier fluid in skin-feel emollients and dry-touch formulations. It is ideal for hair conditioning products where fast evaporation and a non-greasy finish are required. In adhesives and sealants manufacturing, it functions as a solvent for silicone polymers and as a surface primer. The chemical promotes adhesion on low-energy substrates. Plasma-enhanced chemical vapor deposition processes use HMDSO as a precursor to deposit hydrophobic or barrier silica coatings on plastics and films. Hexamethyldisiloxane is supplied as a clear, low-viscosity liquid in drum and IBC quantities. Technical and high-purity grades are available, with purity levels typically ranging from 97% to 99%+. Cosmetic-grade material meeting relevant purity standards is also available for personal care applications. Our supply chain ensures consistent quality and reliable delivery for industrial and laboratory requirements. Contact us for supply of Hexamethyldisiloxane Request Quote

Other Names (Synonyms)

oxybis(trimethylsilane) | HMDSO | bis(trimethylsilyl) oxide | bis(trimethylsilyl) ether | ((CH3)3Si)2O | Disiloxane, hexamethyl- | Fluka AG | Belsil DM 0.65

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-66 °C
Boiling Point99.5 °C
Density0.7638 g/cm³ @ Temp: 20 °C
Flash Point33 °F
AppearanceColorless or yellowish transparent liquid
ColorColorless to Almost colorless
Formliquid
Water Solubilityinsoluble
Vapor Pressure20 hPa (20 °C)
Refractive Indexn 20/D 1.377(lit.)
Log P5.06 at 20℃

Safety & Handling

Danger
GHS02· FlammableGHS09· EnvironmentGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H225Highly Flammable liquid and vapor
H315Causes skin irritation
H332Harmful if inhaled
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P391Collect spillage.
P501Dispose of contents/container in accordance with local regulations.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.

Trade & Regulatory

HS Code29310095
UN Number1993
ADR Class3
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)3