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Menatetrenone

CAS Number
863-61-6
EC Number
234-264-5
Chemical Formula
C31H40O2
Molecular Weight
444.6 g/mol

Description

Menatetrenone (CAS 863-61-6 ), commercially recognized as MK-4 and Menaquinone-4, is the synthetic short-chain form of Vitamin K2 used across pharmaceutical, nutraceutical, and functional food applications. It supports calcium metabolism regulation and bone health positioning in finished products, making it a target active ingredient for formulators developing condition-specific supplements. In pharmaceutical manufacturing, menatetrenone is the active ingredient in prescription bone-health therapeutics, particularly in markets such as Japan where it holds approved drug status. Nutraceutical and dietary supplement producers incorporate MK-4 into softgels, tablets, and combination bone-health formulas alongside Vitamin D3 and calcium for maximum efficacy. Functional food and fortified beverage manufacturers use it to support on-pack K2 content claims, particularly in dairy and plant-based formats. Cosmetic formulators have explored its antioxidant activity. Menatetrenone is supplied as a yellow to orange crystalline powder or in oil-based dispersion formats suited to encapsulation and liquid filling. Pharmaceutical-grade material is available to USP specifications. Food- and supplement-grade material is also offered, with standardized concentrations common in premix and microencapsulated forms for improved stability in finished formulations. Contact us for supply of Menatetrenone Request Quote

Other Names (Synonyms)

Vitamin MK 4 | MK4 | Menaquinone K4 | menaquinone 4 | K2 MK4 | 2-Methyl-3-trans-tetraprenyl-1,4-naphthoquinone | 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone | Kaytwo | MK-4

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point35 °C
Boiling Point494.59°C (rough estimate)
Density1.0461 (rough estimate)
Flash Point2°C
AppearanceYellow Crystals
ColorLight Yellow to Yellow
Formneat
Refractive Index1.5045 (estimate)

Trade & Regulatory

HS Code2914699000
UN Number1648
ADR Class3
Packing GroupII
Storage Class11 - Combustible Solids
WGK (Germany)3