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Phylloquinone

CAS Number
84-80-0
EC Number
201-564-2
Chemical Formula
C31H46O2
Molecular Weight
450.7 g/mol

Description

Phylloquinone (CAS 84-80-0 ), commercially recognized as Vitamin K1, is the naturally occurring form of vitamin K derived primarily from plant sources. It functions as a bioactive nutrient in food fortification and pharmaceutical formulations. This compound is also utilized in cosmetic preparations where coagulation-related and skin-conditioning activity is required. In pharmaceutical manufacturing, it is formulated into injectable solutions, oral capsules, and tablets. These products target vitamin K deficiency and anticoagulant reversal protocols. Food and infant formula producers use it to fortify products to meet regulatory nutrient reference values across major global markets. In cosmetic formulations, it is incorporated into eye creams, serums, and post-procedure skincare products. These applications target the appearance of dark circles and bruising through topical delivery systems. Clinical nutrition manufacturers also include it in parenteral and enteral nutrition products requiring complete micronutrient profiles. It is supplied as a viscous oil in its pure form for various industrial uses. Emulsified and water-dispersible formats are available for aqueous formulation systems. Standard grades include USP , BP , and Ph. Eur. , supporting pharmaceutical and clinical nutrition applications. Food-grade material meeting FCC specifications is available for dietary supplement and fortified food production. This ensures compliance with international safety and quality standards for human consumption. Contact us for supply of Phylloquinone Request Quote

Other Names (Synonyms)

Vitamin K1 | Vitamin k | trans-Phylloquinone | Synthex P | Phythyl-menadion | Monodion | Mono-Kay | Mephyton

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-20 °C
Boiling Point140-145 °C @ Press: 1 x 10-3 Torr
Density0.964 g/cm³ @ Temp: 25 °C
Flash Point>230 °F
AppearancePhylloquinone is an odorless yellow viscous oil or crystals.
ColorYellow to Dark Yellow
Odorodorless
Formviscous liquid
Water SolubilityMiscible with dehydrated alcohol, acetone, petroleum ether, hexane, dioxane, chloroform, ether, benzene and vegetable oils. Immiscible with water.
Refractive Indexn 20/D 1.527(lit.)
Log P10.305 (est)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H317May cause an allergic skin reaction
H413May cause long lasting harmful effects to aquatic life

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P501Dispose of contents/container in accordance with local regulations.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.

Trade & Regulatory

HS Code29369000
UN Number1170
Packing GroupII
Storage Class10 - Combustible liquids
WGK (Germany)2