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Glycine hydrochloride

CAS Number
6000-43-7
EC Number
227-841-8
Chemical Formula
C2H5NO2.ClH
Molecular Weight
111.53 g/mol

Description

Glycine hydrochloride (CAS 6000-43-7 ), also known as aminoacetic acid hydrochloride, is the hydrochloride salt form of glycine used across pharmaceutical, food, and personal care manufacturing. It functions primarily as a pH buffer and acidulant in formulations where precise, stable acidic conditions are required. In pharmaceutical manufacturing, it serves as a buffering agent in parenteral formulations. This material is essential for lyophilized drug products and API synthesis where controlled pH is critical to product stability. Food and nutrition producers use it to adjust acidity in functional food systems. It also acts as a preservation aid where mild antimicrobial activity is needed at low pH. Personal care formulators incorporate it into skin-conditioning products to support moisture retention. Its hygroscopic character is beneficial in both leave-on and rinse-off formats. It also appears in peptide synthesis workflows as a protected amino acid precursor for specialty chemical and biotech procurement. The product is supplied as a white crystalline powder. Pharmaceutical-grade material is available to USP and BP specifications, supporting regulated drug product manufacturing requirements. Technical and reagent grades are also commercially available for industrial synthesis and laboratory applications. This ensures versatility across various industrial sectors and research environments globally. Contact us for supply of Glycine hydrochloride Request Quote

Other Names (Synonyms)

Aminoacetic acid hydrochloride | Glycocoll hydrochloride | 225ZLC74HX | Hydrochloride, Glycine | RefChem:143839 | Glycine, hydrochloride (1:1) | Carboxymethanaminium chloride

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point184-185 °C
Density1.457[at 20℃]
Appearancewhite crystals or crystalline powder
ColorWhite to almost white
FormCrystalline Powder
Water SolubilitySLIGHTLY SOLUBLE
Vapor Pressure0.003Pa at 20℃
Log P-3.25 at 20℃

Safety & Handling

Danger
GHS05· CorrosiveGHS07· Irritant

Hazard Statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224999
UN Number1789
ADR Class8
Packing GroupIII
WGK (Germany)2