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Palmitoylethanolamide

CAS Number
544-31-0
EC Number
208-867-9
Chemical Formula
C18H37NO2
Molecular Weight
299.5 g/mol

Description

Palmitoylethanolamide (CAS 544-31-0 ), commonly abbreviated as PEA, is a fatty acid amide produced from palmitic acid and ethanolamine. Known in industrial contexts as palmitic acid monoethanolamide, it functions as a surface-active agent and emulsifier. This versatile compound is utilized across pharmaceutical and personal care manufacturing. In pharmaceutical formulations, PEA is incorporated as an active ingredient in oral and topical dosage forms where high purity is required. Regulatory-grade purity and consistent particle size are critical sourcing criteria for manufacturers. Personal care producers use it as an emulsifier and foam stabilizer in cleansing systems, shampoos, and skin creams. The material contributes significantly to texture and product stability in various applications. In cosmetic formulations, it supports emulsification of oil-water systems, reducing the need for additional co-emulsifiers. Industrial surface treatment processes use palmitic acid monoethanolamide as a wetting and dispersing agent. These properties help to improve substrate adhesion and coating uniformity in specialized manufacturing environments. The product is supplied as a white to off-white powder or waxy solid. Pharmaceutical and nutraceutical applications are served by micronized and ultramicronized grades to meet specific formulation needs. These grades differ in particle size distribution and bioavailability profile, which is a key specification decision for formulators. Technical and cosmetic grades are also available for non-pharmaceutical applications. Our supply chain ensures that all batches meet rigorous quality standards such as USP and EP . This ensures reliability for global manufacturers seeking consistent performance in their chemical raw materials. Contact us for supply of Palmitoylethanolamide Request Quote

Other Names (Synonyms)

Palmitoyl-EA | Palmitinsaeure-beta-hydroxyethylamid | Palmitic acid monoethanolamide | Palmitamide MEA | N-Hexadecyl-ethanolamine | N-hexadecanoylethanolamine | N-(2-Hydroxyethyl)palmitamide | N-(2-Hydroxyethyl)hexadecanamide | PEA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point98.5 °C
Boiling Point461.5±28.0 °C(Predicted)
Density0.910±0.06 g/cm3(Predicted)
ColorWhite
FormWhite solid
Water Solubility4.01mg/L at 20℃
Vapor Pressure0.45Pa at 20℃
Log P3.989 at 20℃

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS09· Environment

Hazard Statements

H315Causes skin irritation
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P264Wash … thoroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P321Specific treatment (see … on this label).
P391Collect spillage.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2934.99.4400
UN Number3077
WGK (Germany)2