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Dehydroacetic acid

CAS Number
520-45-6
EC Number
208-293-9
Chemical Formula
C8H8O4
Molecular Weight
168.15 g/mol

Description

Dehydroacetic acid (CAS 520-45-6 ), also known by its food additive designation E265 , is a broad-spectrum antimicrobial and preservative active against fungi, yeasts, and bacteria. DHA is used across food, cosmetic, and pharmaceutical manufacturing to extend shelf life and maintain product integrity. In personal care and cosmetics, it is commonly paired with benzyl alcohol as a preservative system. This combination is used in creams, lotions, and rinse-off products, offering effective protection at low use levels. Food manufacturers apply it as a surface preservative on cut vegetables, fruit, and bakery goods. In these applications, mold inhibition is the primary concern for the manufacturer. In pharmaceutical manufacturing, it functions as a preservative in topical formulations and semi-solid preparations requiring fungistatic protection. Cosmetic formulators also use it in leave-on products where paraben-free preservation is a formulation requirement. Dehydroacetic acid is supplied as a white to off-white crystalline powder for industrial use. Standard commercial grades include food-grade material meeting E265 specifications and cosmetic-grade material aligned with supplier-specific purity requirements. Pharmaceutical-grade material is available from select manufacturers. The purity of these high-grade materials is typically stated at 99% or higher. This ensures compliance with various global regulatory frameworks and safety standards for sensitive consumer applications. Contact us for supply of Dehydroacetic acid Request Quote

Other Names (Synonyms)

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one | RefChem:761396 | GlyTouCan:G82156FZ | G82156FZ | 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione | 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl- | Biocide 470F | Acetic acid, dehydro- | DHA | E265

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point109 °C
Boiling Point269.9 °C @ Press: 760 Torr
Density1.1816 (rough estimate)
Flash Point157°C
Appearancewhite to light yellow crystal powder
ColorLight yellow or cream
Odoralmost odorless. slightly bitter-sweet taste.
FormFine Crystalline Powder
Water Solubility500mg/L at 25℃
Vapor Pressure0.001 hPa (20 °C)
Refractive Index1.4611 (estimate)
pH4 (2g/l, H2O, 20℃)
Log P0.78 at 20℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P330Rinse mouth.
P501Dispose of contents/container in accordance with local regulations.
P317Get emergency medical help.

Trade & Regulatory

HS Code29322980
WGK (Germany)1