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Aminoguanidine hydrochloride

CAS Number
1937-19-5
EC Number
217-707-7
Chemical Formula
CH6N4.ClH
Molecular Weight
110.55 g/mol

Description

Aminoguanidine hydrochloride (CAS 1937-19-5 ), also known as Pimagedine hydrochloride, is a reactive guanidine derivative used primarily as a pharmaceutical intermediate and biochemical research reagent. It functions as a carbonyl-trapping agent and selective inhibitor in synthetic and biological systems, making it a critical building block in drug development workflows for global manufacturers. In pharmaceutical synthesis, it serves as a key intermediate in the preparation of heterocyclic compounds, including triazines, aminotriazoles, and guanidine-based active pharmaceutical ingredients. Biotechnology researchers use it to study advanced glycation end-product formation, where its carbonyl-scavenging activity is central to mechanistic assays and compound screening programs. It also functions as a catalyst or reactive intermediate in the synthesis of specialty agrochemical and fine chemical targets requiring guanidine scaffolds for specific industrial applications. Contract manufacturers and API producers source it as a starting material for multi-step synthesis routes targeting cardiovascular and metabolic disease candidates in clinical development. Aminoguanidine hydrochloride is supplied as a white to off-white crystalline powder. It is available in research-grade and technical-grade specifications with high-purity grades commonly supplied. Packaging ranges from small laboratory quantities to multi-kilogram industrial lots depending on application requirements, ensuring reliable supply for both R&D and large-scale production. Contact us for supply of Aminoguanidine hydrochloride Request Quote

Other Names (Synonyms)

Pimagedine hydrochloride | Aminoguanidine hcl | 2-aminoguanidine;hydrochloride | Aminoguanidinium chloride

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point160-162 °C
Appearancewhite to off-white crystals
ColorWhite to off-white
FormCrystals
Water Solubility506.7g/L at 20℃
Vapor Pressure0Pa at 25℃
Log P-3.55 at 20℃

Safety & Handling

Danger
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29280000
Storage Class13 - Non Combustible Solids
WGK (Germany)3