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Pharmaceutical Intermediates REACH

2-naphthol

CAS Number
135-19-3
EC Number
205-182-7
Chemical Formula
C10H8O
Molecular Weight
144.17 g/mol
Industries:Printing & PackagingTextile, Leather & PaperPersonal Care & Cosmetics

Description

2-Naphthol (CAS 135-19-3 ), also known as Developer BN and Naphthol B, is an aromatic alcohol used as a key chemical intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. It functions as a coupling component in azo chemistry and as a preservative and antioxidant in select industrial formulations. In textile and leather processing, it is applied directly to fiber as a diazo coupling base. This enables the on-fiber formation of fast azo dyes with strong wash resistance. Pigment manufacturers use it to produce azo pigment reds and lakes widely specified in printing inks and packaging coatings. In pharmaceutical manufacturing, it serves as a starting material for synthesis of antifungal actives and other API intermediates. Personal care formulators have historically used it for its preservative properties. It also provides antioxidant properties in specific topical applications, though regulatory acceptance varies by market. The material is supplied as a white to off-white crystalline solid or flake. Technical grade is the standard commercial form, with pharmaceutical-grade material available to meet BP and USP specifications. Packaging typically ranges from 25 kg bags or drums to bulk quantities. Contact us for supply of 2-naphthol Request Quote

Other Names (Synonyms)

Trimetin | Naphthol b | Developer BN | beta.-Hydroxynaphthalene | beta-Napthol | beta-Naphtol | beta-Naphthyl hydroxide | beta-Naphthyl alcohol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point121.6 °C
Boiling Point285 °C
Density1.28 g/cm³ @ Temp: 20 °C
Flash Point153 °C
Appearance2-Naphthol is a white, crystalline solid. Slight phenolic odor. Darkens in air and on exposure to light.
ColorWhite
Odorfaint phenol-like odor
FormPowder, Crystals or Granules
Water Solubility1 g/L (20 ºC)
Vapor Pressure10 mm Hg ( 145.5 °C)
Refractive Index1.5762 (estimate)
Log P1.89 at 20℃

Safety & Handling

Warning
GHS07· IrritantGHS09· EnvironmentGHS05· CorrosiveGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H370Causes damage to organs
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H401Toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects H302+
H332Harmful if swallowed or if inhaled

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29071590
UN Number3077
ADR Class9
Packing GroupIII
Storage Class11 - Combustible Solids
WGK (Germany)2