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Amines REACH

Spermidine

CAS Number
124-20-9
EC Number
204-689-0
Chemical Formula
C7H19N3
Molecular Weight
145.25 g/mol

Description

Spermidine (CAS 124-20-9 ), also abbreviated as SPD, is a naturally occurring polyamine sourced from plant and microbial origins, available in both synthetic and natural-extract forms. In commercial supply, it functions as a bioactive ingredient targeting cellular renewal pathways, a biochemical reagent in research workflows, and a functional additive in premium formulations. In cosmetics and personal care, SPD is incorporated into anti-aging serums and scalp treatments where it supports hair follicle longevity and skin renewal at the cellular level. Pharmaceutical and nutraceutical manufacturers use it as the active ingredient in longevity-focused dietary supplements, capsules, and functional foods — a fast-growing category driven by autophagy research. In biotechnology, spermidine is a critical reagent in cell culture media, nucleic acid stabilization protocols, and enzyme activity studies for various laboratory applications. Food-grade applications include functional food fortification, where wheat germ extract standardized to spermidine content is the most commercially established delivery format for manufacturers. Spermidine is supplied as a trihydrochloride salt in powder form, which offers improved stability over the free base. Standard grades include research-grade (high-purity ≥98%) and cosmetic/nutraceutical-grade material. Wheat germ extract standardized to defined spermidine content is also commercially available as a natural-source alternative for food and supplement applications meeting specific quality requirements. Contact us for supply of Spermidine Request Quote

Other Names (Synonyms)

Spermidin | N-(gamma-Aminopropyl)tetramethylenediamine | N-(4-Aminobutyl)-1,3-diaminopropane | N-(3-aminopropyl)butane-1,4-diamine | N-(3-Aminopropyl)-4-aminobutylamine | N-(3-Aminopropyl)-1,4-diaminobutane | N-(3-Aminopropyl)-1,4-butanediamine | 4-Azaoctane-1,8-diamine | SPD

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point<25 °C
Boiling Point128-130 °C
Density1.00054 g/cm³ @ Temp: 45 °C
Flash Point>230 °F
AppearanceColorless clear liquid
ColorClear colorless
OdorIchtyal, ammoniacal
FormLiquid After Melting
Water SolubilityMiscible with water, ethanol and ether.
Refractive Indexn 20/D 1.479(lit.)
pH12.0-13.5 (25℃, 1M in H2O)

Safety & Handling

Danger
GHS05· Corrosive

Hazard Statements

H314
H314
H318H318

Precautionary Statements

P260
P260
P264
P264
P280
P280
P316
P316
P317
P317
P321
P321
P363
P363
P405
P405
P501
P501
P265
P265
P340
P340
P331
P331
P354
P354
P338

Trade & Regulatory

HS Code29212900
UN Number2735
ADR Class8
Packing GroupII
WGK (Germany)3