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Pyrithione

CAS Number
1121-31-9
EC Number
214-329-4
Chemical Formula
C5H5NOS
Molecular Weight
127.17 g/mol

Description

Pyrithione (CAS 1121-31-9 ), also known as Omadine, is a broad-spectrum antimicrobial active used across industrial and personal care markets. It functions as a biocide and preservative, targeting bacteria, fungi, and algae. In personal care, it is the active ingredient in anti-dandruff shampoos and scalp treatments, where it controls the fungal growth responsible for dandruff. It is essential for maintaining product integrity and efficacy. Coatings and marine antifouling systems rely on it to prevent microbial and algal buildup on surfaces exposed to moisture or immersion. This ensures long-term protection for various industrial and maritime applications. In water treatment, it controls microbial contamination in industrial process water, cooling towers, and recirculating systems. This helps maintain system efficiency and prevents the buildup of harmful biological films. Adhesives, sealants, and elastomers incorporate it as an in-can or dry-film preservative to extend product shelf life. This prevents microbial degradation during storage and ensures the material remains stable over time. The material is supplied as a crystalline powder and in aqueous solution form, with concentration levels varying by application requirement. It is available in technical and industrial grades for diverse uses. Purity specifications are available suited for pharmaceutical and personal care use, often meeting USP or Ph.Eur. standards. Zinc and sodium salt forms are the most commercially traded derivatives. Zinc Pyrithione and Sodium Pyrithione are sourced separately based on formulation compatibility and specific performance needs. These derivatives offer versatile solutions for modern chemical manufacturing and preservation. Contact us for supply of Pyrithione Request Quote

Other Names (Synonyms)

Pyridinethiol N-oxide | pyridine-2-thiol-1-oxide | Omadine | 2-pyridinethiol, 1-oxide | 2-mercaptopyridine-N-oxide | 2-mercaptopyridine monoxide | 1-oxido-2-pyridinyl hydrosulfide | 1-Hydroxy-2-pyridinethione

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point70-73 °C
Boiling Point350.2±15.0 °C(Predicted)
Density1.255 (estimate)
Appearanceoff-white powder
ColorOff-white to beige or yellow to yellow-greenish or grayish-green
FormPowder, Crystals, and/or Chunks
Refractive Index1.5480 (estimate)

Safety & Handling

Danger
GHS06· ToxicGHS07· Irritant

Hazard Statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29333990
WGK (Germany)3