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Solvents REACH

Diethylene glycol dimethyl ether

CAS Number
111-96-6
EC Number
203-924-4
Chemical Formula
C6H14O3
Molecular Weight
134.17 g/mol

Description

Diethylene glycol dimethyl ether (CAS 111-96-6 ), commercially known as Diglyme, is a high-boiling aprotic ether solvent used across pharmaceutical synthesis and polymer processing. Its controlled evaporation rate and strong solvating power make it a preferred solvent where lower-boiling alternatives fail to maintain process stability during specialty chemical manufacturing. In pharmaceutical manufacturing, Diglyme functions as a reaction solvent for Grignard reactions, metal hydride reductions, and other moisture-sensitive syntheses requiring an inert, coordinating medium. Polymer formulators use it as a polymerization solvent and chain-transfer agent in the production of specialty resins and adhesives for industrial applications. In battery electrolyte research and lithium-ion cell development, it serves as a co-solvent that improves ionic conductivity and electrode compatibility for advanced energy storage. Biotechnology applications include its use as a carrier solvent in reagent formulations where consistent solvation and low reactivity with biological substrates are required. Diglyme is supplied as a clear liquid in drum, IBC, and bulk quantities. Technical grade is the standard offering for industrial and research applications across the global market. Anhydrous and high-purity grades are available to meet pharmaceutical and battery-grade specifications. Packaging options typically range from laboratory-scale containers to full bulk tanker supply. Contact us for supply of Diethylene glycol dimethyl ether Request Quote

Other Names (Synonyms)

Diethylene glycol dimethylether | 1-methoxy-2-(2-methoxyethoxy)ethane | Diglyme

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-68 °C
Boiling Point162 °C @ Press: 760 Torr
Density0.9451 g/cm³ @ Temp: 20 °C
Flash Point134.6 °F
AppearanceColorless clear liquid
Color≤10(APHA)
OdorMild ethereal.
FormLiquid
Water SolubilityMiscible
Vapor Pressure3 mm Hg ( 20 °C)
Refractive Indexn 20/D 1.408(lit.)
pH7 (20°C)
Log P-0.36 at 25℃

Safety & Handling

Danger
GHS02· FlammableGHS08· Health HazardGHS07· Irritant

Hazard Statements

H226Flammable liquid and vapor
H303May be harmful if swallowed
H316Causes mild skin irritation
H320Causes eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29091900
UN Number3271
ADR Class3
Packing GroupIII
Storage Class3 - Flammable liquids
WGK (Germany)1