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Alpha lipoic acid

CAS Number
1077-28-7
EC Number
214-071-2
Chemical Formula
C8H14O2S2
Molecular Weight
206.3 g/mol

Description

Alpha lipoic acid (CAS 1077-28-7 ) is a sulfur-containing antioxidant compound used across pharmaceutical, nutraceutical, and cosmetic manufacturing. It functions primarily as an antioxidant and cellular cofactor. The material is used in both finished dosage forms and active ingredient formulations. In nutraceuticals and dietary supplements, it is formulated into capsules, tablets, and functional foods targeting metabolic support. Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports oxidative stability. Its skin-conditioning performance makes it a versatile choice for high-end topical applications. Pharmaceutical manufacturers use it as an active ingredient in intravenous and oral preparations. This is common in markets where it holds drug status for specific neuropathic indications and therapeutic uses. In food-grade applications, it is evaluated as an antioxidant stabilizer in fortified products and functional beverage systems. It helps maintain the integrity of complex formulations during the manufacturing process. The product is supplied as a fine crystalline yellow powder. Standard grades include pharmaceutical-grade material meeting USP and Ph. Eur. specifications for global compliance and safety. Food-grade and cosmetic-grade options are also available for non-pharmaceutical applications. Bulk quantities are provided for industrial-scale formulation to meet the demands of large-scale production facilities. R-alpha lipoic acid is also available as a distinct enantiomer-specific grade for premium supplement applications. This specialized version offers targeted benefits for manufacturers seeking high-potency ingredients. Contact us for supply of Alpha lipoic acid Request Quote

Other Names (Synonyms)

liponic acid | acetate-replacing factor | 6,8-thiotic acid | 6,8-thioctic acid | 6-thiotic acid | 6-thioctic acid | 5-[3-(1,2-dithiolanyl)]pentanoic acid | 5-(dithiolan-3-yl)pentanoic acid | ALA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point60-61 °C
Boiling Point160-165 °C
Density1.2888 (rough estimate)
Flash Point160-165°C
AppearanceLight-Yellow Solid
ColorYellow
FormCrystals or Crystalline Powder
Water Solubility0.9 g/L (20 ºC)
Refractive Index1.5200 (estimate)
Log P2.530 (est)

Safety & Handling

Warning
GHS07· IrritantGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29349900
Storage Class11 - Combustible Solids
WGK (Germany)3