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D-alanine

CAS Number
338-69-2
EC Number
206-418-1
Chemical Formula
C3H7NO2
Molecular Weight
89.09 g/mol

Description

D-Alanine (CAS 338-69-2 ), also known as D-Ala, is the D-enantiomer of the naturally occurring amino acid alanine. It functions as a chiral building block, buffering agent, and stabilizer across pharmaceutical and cosmetic applications. Demand is driven primarily by its role in synthesizing peptide-based active ingredients and pharmaceutical intermediates where enantiomeric purity is critical. In pharmaceutical manufacturing, it is used as a chiral intermediate. It is essential in the synthesis of peptide antibiotics, enzyme inhibitors, and other stereospecific active compounds. Cosmetic formulators incorporate it into skin care products for its moisturizing and pH-buffering properties. It is particularly effective in serums and treatment creams targeting hydration. In food and nutrition, it functions as a flavor modifier and stabilizer in specialty formulations, including amino acid-enriched dietary supplements. Research and peptide synthesis laboratories also source it as a building block for custom peptide sequences requiring non-natural amino acid incorporation. This versatility makes it a staple in modern chemical synthesis. The product is supplied as a white crystalline powder. It is available in pharmaceutical-grade ( USP / BP ) and reagent-grade specifications to meet the purity requirements of different industrial end markets. Packaging ranges from small quantities for laboratory and R&D use to bulk quantities for industrial peptide synthesis. We ensure high-quality standards for commercial formulation and large-scale manufacturing needs. Contact us for supply of D-alanine Request Quote

Other Names (Synonyms)

(2R)-2-aminopropanoic acid | D-2-Aminopropionic acid | D-Ala | D-alpha-Alanine | Alanine, D- | Alanine D-form | (R)-2-Aminopropionic acid | Ba 2776

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point292 °C
Boiling Point212.9±23.0 °C(Predicted)
Density1.4310 (estimate)
AppearanceWhite Crystalline Powder
ColorWhite to off-white
Odorodorless
FormCrystalline Powder or Crystals
Water Solubility155 g/L (20 ºC)
Refractive Index-14 ° (C=2, 6mol/L HCl)
Log P-0.574 (est)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224900
Storage Class11 - Combustible Solids
WGK (Germany)3