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Isethionic acid

CAS Number
107-36-8
EC Number
203-484-3
Chemical Formula
C2H6O4S
Molecular Weight
126.13 g/mol

Description

Isethionic acid (CAS 107-36-8 ) is a sulfonic acid derivative used primarily as a chemical intermediate and pH buffering agent across pharmaceutical, personal care, and industrial manufacturing sectors. Its sodium and potassium salts, sodium isethionate and potassium isethionate, are independently traded and specified in formulation work, making them distinct procurement targets for global manufacturers. In personal care manufacturing, these compounds serve as key intermediates in synthesizing acyl isethionate surfactants, the basis of mild, skin-compatible cleansing bars and liquid wash systems. Pharmaceutical formulators use it as a buffering agent and solvent carrier in drug salt formation, particularly where improved solubility or controlled pH is required for stability. Textile and leather processors apply it in dyeing and finishing baths, where its buffering capacity helps maintain consistent process pH and improves dye uptake uniformity across materials. Paper treatment operations use isethionate salts as dispersing agents to improve fiber compatibility and surface chemistry. Isethionic acid is supplied as an aqueous solution, typically around 70% concentration. Sodium isethionate is available as a white powder or granules, commonly offered in technical and cosmetic-grade specifications. Potassium isethionate is available from specialty suppliers in technical-grade form. Contact us for supply of Isethionic acid Request Quote

Other Names (Synonyms)

Sodium beta-hydroxyethanesulfonate | Potassium isethionate | Potassium 2-hydroxyethanesulfonate | Kyselina isethionova | Isethionic acid sodium salt | Hydroxyethylsulfonic acid | Ethanolsulfonic acid | beta-hydroxyethanesulfonic acid

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point<25 °C
Boiling Point226°C at 101.3kPa
Density1.344 (estimate)
AppearanceLiquid. Very soluble in water
insoluble in alcohol.
ColorColorless to light yellow
FormColourless Solution
Vapor Pressure0Pa at 25℃
Refractive Index1.5090 (estimate)
Log P-1.65 at 25℃ and pH2

Safety & Handling

Danger
GHS05· Corrosive

Hazard Statements

H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P321Specific treatment (see … on this label).
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2930909899