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Cellulose acetate phthalate

CAS Number
9004-38-0
EC Number
618-382-8
Chemical Formula
C8H6O4.xC2H4O2.xUnspecified
Molecular Weight
722.6 g/mol

Description

Cellulose acetate phthalate (CAS 9004-38-0 ), commonly abbreviated as CAP, is a cellulose-derived polymer ester used primarily as an enteric coating agent in pharmaceutical manufacturing. It controls the release profile of oral dosage forms by remaining intact in gastric acid while dissolving in the higher pH environment of the intestine. CAP is the material of choice for enteric coating tablets. It is used for capsules and granules where protection from stomach acid is required, particularly for acid-sensitive active pharmaceutical ingredients. It is also used in sustained-release pellet systems. In these systems, coating thickness and polymer concentration determine the dissolution lag time. Formulators incorporate CAP into film-coating solutions alongside plasticizers to achieve consistent coating uniformity. This process is essential at commercial batch scale. Beyond solid dosage forms, it functions as a binder and matrix former in controlled-release granulation processes for various pharmaceutical applications. Cellulose acetate phthalate is supplied as a white to off-white powder. It is available in pharmaceutical-grade specifications meeting USP and Ph. Eur. standards for global compliance. These are the primary grades demanded by regulated drug manufacturers. Suppliers typically offer it in fiber drum or multi-wall bag packaging suited to GMP production environments and large scale logistics. Contact us for supply of Cellulose acetate phthalate Request Quote

Other Names (Synonyms)

Cellulose, acetate hydrogen 1,2-benzenedicarboxylate | RefChem:124308 | NCGC00188441-01 | Cellulose, acetate hydrogen phthalate | Phthalic acid, ester with cellulose acetate | Cellulose acetate-phthalate mixed ester | Cellulose acetophthalate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Appearancewhite granular powder
Formneat

Safety & Handling

Warning
GHS02· FlammableGHS07· Irritant

Hazard Statements

H252Self-heating in large quantities; may catch fire
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P235Keep cool.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P407Maintain air gap between stacks/pallets.
P410Protect from sunlight.
P413Store bulk masses greater than … kg/… lbs at temperatures not exceeding … °C/…°F.
P420Store away from other materials.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code39129010
Storage Class11 - Combustible Solids
WGK (Germany)3