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Solvents REACH

Propylene oxide

CAS Number
75-56-9
EC Number
200-879-2
Chemical Formula
C3H6O
Molecular Weight
58.08 g/mol

Description

Propylene oxide (CAS 75-56-9 ), commonly abbreviated as PO, is a reactive epoxide monomer and industrial solvent used across polymer manufacturing, sterilization, and chemical synthesis. Methyl oxirane is the form referenced in many technical and regulatory contexts as a distinct search term. Its primary commercial role is as a building block for polyols and propylene glycols. PO is the key feedstock for polyether polyols used in polyurethane foam production. This covers rigid insulation panels, flexible seating, and various automotive interiors for industrial manufacturing. In food and pharmaceutical processing, it functions as a fumigant and sterilizing agent for spices and cocoa. It is also used for medical equipment where heat sterilization is not viable. Propylene glycol, produced by hydration of PO, feeds into food-grade humectants and cosmetic carriers. It is also a primary component in modern antifreeze formulations and industrial coolants. In biotechnology, PO is used as a fixative and dehydration agent in electron microscopy sample preparation. It is supplied as a liquid in bulk quantities, typically via ISO tank containers. Standard commercial grades include polymer-grade and technical-grade specifications. Purity levels are commonly at 99.5% or higher for polyol synthesis applications and chemical manufacturing. Buyers sourcing for food or pharmaceutical sterilization applications should confirm compliance with regional regulatory standards. Proper handling is required due to its low boiling point and volatility. Contact us for supply of Propylene oxide Request Quote

Other Names (Synonyms)

propene oxide | methyl oxirane | methyl ethylene oxide | 2,3-epoxypropane | 1,2-propylene oxide | 1,2-epoxy propane | 2-methyloxirane | Oxirane, methyl- | PO

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-112.13 °C
Boiling Point34.23 °C
Density0.8 g/cm³
Flash Point−35 °F
AppearancePropylene oxide is a colorless liquid. Ethereal odor.
ColorClear
OdorEthereal
characteristic
sweet, alcoholyc
like natural gas.
FormLiquid
Water Solubility40 g/100 mL (20 ºC)
Vapor Pressure29.43 psi ( 55 °C)
Refractive Indexn 20/D 1.366(lit.)
Log P0.030

Safety & Handling

Danger
GHS02· FlammableGHS06· ToxicGHS08· Health HazardGHS07· IrritantGHS05· Corrosive

Hazard Statements

H224Extremely flammable liquid and vapor
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H340May cause genetic defects
H341Suspected of causing genetic defects
H350May cause cancer
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29102000
UN Number1280
ADR Class3
Packing GroupI
Storage Class3 - Flammable liquids
WGK (Germany)3