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Amines REACH

Acetamide

CAS Number
60-35-5
EC Number
200-473-5
Chemical Formula
C2H5NO
Molecular Weight
59.07 g/mol

Description

Acetamide (CAS 60-35-5 ), also known as acetic acid amide, is the simplest aliphatic amide and functions as a solvent, plasticizer, and chemical intermediate across pharmaceutical, cosmetic, and biotechnology manufacturing. With FEMA number 4251 , it is recognized in flavoring applications and serves as a building block for synthesis of more complex amide-based compounds in various industrial processes. In pharmaceutical manufacturing, acetamide acts as a reaction intermediate and catalyst precursor in the synthesis of active pharmaceutical ingredients requiring specific amide bond formation during the production cycle. Personal care formulators use it as a humectant and surface-modifying agent in skin conditioning products, where it supports moisture retention at the formulation level for high-quality cosmetic goods. Biotechnology applications include its use as a buffering component and nitrogen source in microbial culture media and biochemical assay systems used for research and development purposes. In specialty chemical synthesis, it functions as a catalyst precursor and pH-regulating agent in controlled reaction environments to ensure consistent results across different manufacturing batches. Acetamide is supplied as a white crystalline solid or powder. Standard commercial grades include technical and pharmaceutical-grade material, with purity levels typically ranging from 98% to 99%+. Packaging is available in laboratory quantities through to bulk industrial supply to meet both R&D and production-scale procurement requirements for global chemical distribution networks. Contact us for supply of Acetamide Request Quote

Other Names (Synonyms)

Acetic acid amide | Acetimidic acid | Ethanimidic acid | Amid kyseliny octove | NCI-C02108 | CH3CONH2

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point81 °C
Boiling Point222 °C @ Press: 760 Torr
Density1.159 g/cm³ @ Temp: 20 °C
Flash Point220-222°C
AppearanceAcetamide is a colorless to yellow, deliquescent, crystalline solid. Odorless if pure, “mousy” odor if impure. Odor threshold5140 160 milligram per cubic meter.
ColorWhite
OdorMousy odor
FormCrystals
Water Solubility2000 g/L (20 ºC)
Vapor Pressure1 mm Hg ( 65 °C)
Refractive Index1.4274
Log P-1.26

Safety & Handling

Warning
GHS08· Health Hazard

Hazard Statements

H316Causes mild skin irritation
H320Causes eye irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29241900
UN Number3077
ADR Class9
Packing GroupIII
Storage Class11 - Combustible Solids
WGK (Germany)1