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Glycyrrhetinic acid

CAS Number
471-53-4
EC Number
207-444-6
Chemical Formula
C30H46O4
Molecular Weight
470.7 g/mol

Description

Glycyrrhetinic acid (CAS 471-53-4 ), also known as uralenic acid, is a pentacyclic triterpenoid derived from licorice root extract. In personal care and cosmetics, it functions as a skin-conditioning active. In flavoring applications, it contributes to the characteristic licorice taste profile of finished products. In cosmetic formulations, it is used in anti-inflammatory creams, serums, and spot-treatment products. Formulators incorporate it into whitening and brightening preparations where it acts as a tyrosinase modulator. This helps to reduce the appearance of hyperpigmentation and redness in various skin types. In the flavor industry, it is used as a flavoring agent and acidulant in confectionery and oral care products. It is also utilized in tobacco flavoring systems where a licorice character is required. It appears in topical pharmaceutical preparations as a functional active in formulations addressing minor skin irritation. The material is supplied as a white to off-white crystalline powder for industrial use. It is available in cosmetic-grade and pharmaceutical-grade specifications, with purity levels typically ranging from 95% to 98% by HPLC. These standards ensure high performance in sensitive applications. Bulk quantities are offered in kilogram and multi-kilogram packaging to suit both development-scale and commercial production requirements. We ensure consistent quality for all global manufacturing needs. Contact us for supply of Glycyrrhetinic acid Request Quote

Other Names (Synonyms)

Uralenic acid | Glycyrrhetic Acid | beta-Glycyrrhetic acid | b-Glycyrrhetic acid | alpha-Glycyrrhetinic acid | a-Glycyrrhetinic acid | 3b-Hydroxy-11-oxoolean-12-en-30-oic acid | 3b-Hydroxy-11-oxoolean-12-en-30-oate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point296 °C
Boiling Point687.4 °C
Density0.9967 (rough estimate)
Appearancewhite or greyish-white crystalline powder
ColorWhite to off-white
FormCrystalline Powder
Water SolubilitySOLUBLE IN ACETIC ACID
Vapor Pressure10-220Pa at 20-50℃
Refractive Index162 ° (C=1, MeOH)
Log P4.5 at 20℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P330Rinse mouth.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29189900
Storage Class11 - Combustible Solids
WGK (Germany)3