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Genistein

CAS Number
446-72-0
EC Number
207-174-9
Chemical Formula
C15H10O5
Molecular Weight
270.24 g/mol

Description

Genistein (CAS 446-72-0 ), also known as Prunetol and Genisteol, is a naturally occurring isoflavone extracted primarily from soy and other leguminous plants. It functions as a phytoestrogen and antioxidant active across pharmaceutical, nutraceutical, and cosmetic applications. Buyers source it both as a purified reference-grade material and as a standardized botanical extract. In nutraceutical and dietary supplement manufacturing, it is formulated into capsules, tablets, and functional foods targeting hormonal balance and bone health support for various consumer demographics. Pharmaceutical developers use it as an intermediate in the synthesis of isoflavone-based compounds and as an active ingredient in investigational formulations requiring high purity and strict quality control. Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports skin surface stabilization and oxidative stress reduction for topical applications. Food-grade applications include fortified beverages and soy-derived functional ingredients where standardized isoflavone content is a key quality parameter for manufacturers and industrial food processors. The material is supplied as an off-white to pale yellow powder in technical and high-purity grades. Standardized extract forms, such as 85% HPLC, are commonly available for formulation work. Reagent and reference-standard grades are also offered to support analytical and pharmaceutical development workflows, ensuring compliance with global chemical and nutritional safety regulations. Contact us for supply of Genistein Request Quote

Other Names (Synonyms)

Prunetol | Genisteol | Differenol A | 5,7,4'-Trihydroxyisoflavone | 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one | 4',5,7-trihydroxyisoflavone | 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point301.5 °C (decomp)
Boiling Point333.35°C (rough estimate)
Density1.2319 (rough estimate)
AppearanceYellow Crystalline Solid
Coloroff-white
Formpowder
Water Solubilityinsoluble
Refractive Index1.6000 (estimate)
Log P3.114 (est)

Safety & Handling

Warning
GHS07· IrritantGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29329900
Storage Class11 - Combustible Solids
WGK (Germany)3