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4-butylresorcinol

CAS Number
18979-61-8
EC Number
606-191-2
Chemical Formula
C10H14O2
Molecular Weight
166.22 g/mol

Description

4-Butylresorcinol (CAS 18979-61-8 ), commercially recognized as Rucinol, is a synthetic depigmentation active used in cosmetic and pharmaceutical formulations. It inhibits tyrosinase and peroxidase enzymes involved in melanin synthesis. This makes it a targeted ingredient for skin-brightening and hyperpigmentation correction products. In premium skincare, it is formulated into serums, creams, and spot treatments targeting melasma and age spots. It is often used at concentrations between 0.1% and 1% for post-inflammatory hyperpigmentation. Pharmaceutical topical preparations use it as an active ingredient in prescription and OTC depigmenting products. Regulatory-grade purity is required for these applications to ensure safety and efficacy. Its antioxidant activity also supports use as a stabilizer in formulations where oxidative degradation is a concern. Some specialty formulations incorporate it for its mild preservative-boosting effect alongside primary systems. 4-Butylresorcinol is supplied as a white to off-white crystalline powder for industrial use. It is available in cosmetic-grade and pharmaceutical-grade specifications. High-purity grades, typically ≥98% or ≥99% by HPLC, are standard for active cosmetic ingredient supply chains. Packaging ranges from small quantities for R&D sampling to kilogram-scale lots for commercial batches. This ensures flexibility for both laboratory development and large-scale manufacturing needs. Contact us for supply of 4-butylresorcinol Request Quote

Other Names (Synonyms)

Rucinol (TN) | 4-butylbenzene-1,3-diol | Rucinol | 1,3-Benzenediol, 4-butyl- | 4-n-Butylresorcinol | Resorcinol, 4-butyl- | 4-Butylresorcin

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point49-50 °C
Boiling Point155-175 °C @ Press: 7 Torr
Density1.092±0.06 g/cm3(Predicted)
Colorwhite to pale yellow powder
OdorCharacteristic
FormPowder
Vapor Pressure0.041Pa at 25℃
Log P2.8 at 24℃ and pH7

Safety & Handling

Warning
GHS07· IrritantGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H400Very toxic to aquatic life

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2907290090
Storage Class13 - Non Combustible Solids
WGK (Germany)2