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Ascorbyl palmitate

CAS Number
137-66-6
EC Number
205-305-4
Chemical Formula
C22H38O7
Molecular Weight
414.5 g/mol

Description

Ascorbyl palmitate (CAS 137-66-6 ), also known by its EU food additive designation E304i , is a fat-soluble ester of vitamin C used commercially as an antioxidant and stabilizer across food, pharmaceutical, and cosmetic manufacturing. Unlike water-soluble ascorbic acid, its lipophilic character makes it effective at protecting oils, fats, and lipid-based systems from oxidative degradation. In food production, it is added to oils, fats, and fat-containing products. Common applications include margarines, baked goods, and infant formula to extend shelf life by retarding rancidity. Pharmaceutical manufacturers incorporate it into lipid-based drug delivery systems and soft gel formulations where oxidation-sensitive active ingredients require protection. In cosmetic and personal care formulations, including creams, serums, and sunscreens, it functions as both an antioxidant preservative and a skin-conditioning agent within emulsion systems. It also serves as a co-emulsifier in lipid dispersions. This functionality improves the stability of oil-in-water systems in both food and topical applications. The material is supplied as a white to yellowish powder or crystalline solid for industrial use. Standard grades include food-grade meeting FCC specifications, as well as USP and Ph.Eur. grades for pharmaceutical applications. These standards ensure the highest level of purity and safety for global distribution. Cosmetic-grade material is also commercially available, with purity typically at or above 98%. This high concentration ensures effective performance in complex chemical formulations and sensitive manufacturing processes. Contact us for supply of Ascorbyl palmitate Request Quote

Other Names (Synonyms)

L-ascorbic acid 6-hexadecanoate | E304i | 6-O-palmitoylascorbic acid | L-Ascorbyl 6-palmitate | L-Ascorbic acid 6-palmitate | Ascorbyl monopalmitate | Ascorbic palmitate | L-Ascorbyl palmitate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point116 °C
Boiling Point512.7±50.0 °C(Predicted)
Density1.150±0.06 g/cm3(Predicted)
ColorWhite to Pale Gray
Odorwh. or yel.-wh. powd., citrus odor
Formneat
Refractive Index22.5 ° (C=1, EtOH)
Log P6.5 at 30℃ and pH1.9

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H319Causes serious eye irritation
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29362700
Storage Class11 - Combustible Solids
WGK (Germany)1