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n-acetylneuraminic acid

CAS Number
131-48-6
EC Number
205-023-1
Chemical Formula
C11H19NO9
Molecular Weight
309.27 g/mol

Description

N-Acetylneuraminic acid (CAS 131-48-6 ), commercially recognized under the abbreviations NeuAc, Neu5Ac, and NANA, is the predominant sialic acid found in mammalian biology. It is a critical building block in glycan chemistry. It functions as a bioactive reference compound, surface modification agent, and functional ingredient across pharmaceutical, cosmetic, and biotechnology supply chains. In pharmaceutical and biotech manufacturing, Neu5Ac serves as a key substrate. It is used as an analytical reference for sialylation studies, glycoprotein characterization, and enzyme assay development. Cosmetic formulators incorporate it into premium skincare products for its moisture-retention properties. It plays a vital role in supporting skin barrier function at the cellular level. In food and nutrition, it is used as a bioactive ingredient in infant formula and functional food products targeting cognitive and immune health. Biotechnology applications include its use as a precursor in the enzymatic or chemical synthesis of sialylated oligosaccharides and therapeutic glycoconjugates. This versatile compound is essential for modern research. N-Acetylneuraminic acid is supplied as a white to off-white crystalline powder. It is available in research-grade and high-purity pharmaceutical-grade specifications, with purity levels typically at 95% or above. GMP -compliant material is available for regulated applications. Packaging ranges from small laboratory quantities to bulk orders suited for industrial formulation and large-scale manufacturing needs. Contact us for supply of n-acetylneuraminic acid Request Quote

Other Names (Synonyms)

NeuAc | Neu5Ac | NANA | N-acetyl-beta-neuraminic acid | beta-Neu5Ac | TIP79W5HPN | N-acetyl-beta-D-neuraminic acid | GlyTouCan:G76571JT

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point182-184 °C
Boiling Point449.56°C (rough estimate)
Density1.3580 (rough estimate)
AppearanceCrystalline
ColorWhite to Off-White
Formsynthetic, crystalline
Water Solubility50 g/L (20 ºC)
Refractive Index-32 ° (C=1, H2O)
Log P-1.897 (est)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H319H319

Precautionary Statements

P280
P280
P265
P265
P317
P317
P338

Trade & Regulatory

HS Code29329900
Storage Class11 - Combustible Solids
WGK (Germany)3