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Chlorphenesin

CAS Number
104-29-0
EC Number
203-192-6
Chemical Formula
C9H11ClO3
Molecular Weight
202.63 g/mol

Description

Chlorphenesin (CAS 104-29-0 ), also known as p-chlorophenyl-alpha-glyceryl ether, is a synthetic antimicrobial active used across cosmetic and pharmaceutical formulations. It functions as a preservative and biocide, inhibiting microbial growth to extend product shelf life. In personal care, this compound is used as a preservative in rinse-off and leave-on products including moisturizers, cleansers, and hair care formulations. It is often used in combination with other preservatives to broaden the antimicrobial spectrum. Pharmaceutical manufacturers incorporate it into topical preparations where controlled microbial protection is required without the regulatory burden of more restricted preservative systems. Its compatibility with a range of cosmetic actives makes it a practical option. Formulators developing paraben-free preservation systems frequently select this ingredient for its stability and efficacy. It is also evaluated as a pharmaceutical intermediate in select synthesis pathways targeting chlorinated glycerol ether derivatives. The material is supplied as a white crystalline powder. Standard market grades include cosmetic/personal care grade and pharmaceutical-grade material, with suppliers typically offering documentation aligned to USP or in-house specifications. Packaging is available in kilogram quantities for development use through to bulk supply for commercial manufacturing. This ensures that both small-scale laboratories and large industrial facilities can source the material according to their specific production needs. Contact us for supply of Chlorphenesin Request Quote

Other Names (Synonyms)

P-Chlorophenyl-alpha-glyceryl ether | Glycerol alpha-P-chlorophenyl ether | Chlorphénésine | 3-(P-Chlorophenoxy)propane-1,2-diol | 3-(P-Chlorophenoxy)-1,2-propanediol | 3-(4-Chlorophenoxy)-1,2-propanediol | 3-(4-chlorophenoxy)propane-1,2-diol | 1,2-Propanediol, 3-(4-chlorophenoxy)-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point78 °C
Boiling Point290.96°C (rough estimate)
Density1.2411 (rough estimate)
ColorWhite to Off-White
FormSolid
Water SolubilitySlightly soluble in water.
Vapor Pressure0Pa at 25℃
Refractive Index1.5470 (estimate)
Log P1.23 at 23℃

Safety & Handling

Danger
GHS05· CorrosiveGHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29094990